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The Y161F Substitution of Hemagglutinin Increases Antigenic Thermostability and Improves Yields of Influenza A Viruses

Published: 9/6/2024

Inventor(s): Xiu-Feng (Henry) Wan, Feng Wen

Background Vaccination has been the most efficient and economical strategy for preventing influenza virus infection and controlling disease spread among hosts. A high yield vaccine seed strain is required for timely vaccine manufacture and is thus a critical component of a successful influenza vaccination program. Unfortunately, it is not uncommon...

Reagents, Devices, and Accessories for Kinetic Fluorogenic Chemical Quantification

Published: 11/4/2024

Inventor(s): Dongmao Zhang, Max Wamsley

Background Kinetic chromogenic (CG) and fluorogenic (FG) quantification deduces analyte concentration based on the reaction rate between the CG/FG probe and its targeted molecule. Little progress has been made in the past half century in either the theory or the applications of the kinetic spectroscopic quantification methods. Current kinetic CG/FG...

A Method for Targeting Nanoparticles to Bacterial Biofilm Infections using Bacterial Surface Proteins

Published: 10/2/2024

Inventor(s): Nicholas Fitzkee, Dhanush Amarasekara

Background Biofilm‑related infections are associated with high mortality and morbidity, combined with increased hospital stays and overall treatment costs. Traditional antibiotics play an essential role in controlling biofilms; however, they are becoming less effective due to the emergence of drug‑resistant bacterial strains. The need to treat biofilms...

A rapid assay for detecting neutralizing antibody against Sars-Cov2

Published: 10/16/2023

Inventor(s): Keun Seok Seo, Nogi Park, Joo Youn Park

Overview of Technology:­ Aims to develop a test that determines if a person contains a neutralizing or non-neutralizing antibody against the SARS-Cov2 virus Background on Technology: SARS-CoV-2 expresses a unique spike protein that interacts with human angiotensin-converting enzyme 2 (ACE2) for invading human respiratory epithelial cells. Studies...

2.0 mm, double fenestrated, titanium bone anchors

Published: 1/13/2023

Inventor(s): Andy Shores

Overview of Technology A device for the stabilization, alignment, and compression of atlanto-axial vertebral luxations using very small instrumentation. Description of Technology Researchers at Mississippi State University have developed a technology that is used as a surgical implant to repair dislocation of vertebrae in animals. The anchors are...

3CAM- 3-Dimensional Calcified Arterial Model

Published: 8/29/2023

Inventor(s): C. Simpson

Overview of Technology A three-dimensional bench top model for diseased arteries that would change the way cardiovascular research is conducted. Description of Technology Researchers at Mississippi State University have developed a technology that is composed of a three-dimensional bench top model for diseased arteries that would change the way...