Search Results - veterinary+medicine 8 Results Sort By: Published Date Updated Date Title ID Descending Ascending Compositions and Methods for inducing Immune Response Against Staphylococcus Aureus Causing Bovine Mastitis Published: 2/4/2025 Inventor(s): Keun Seok Seo, Dong Chan Moon Background Bovine mastitis is a significant economic burden in the U.S. dairy industry estimating $2 billion loss annually. Bovine mastitis caused by Staphylococcus aureus is highly contagious, resistant to many antibiotics, and often resulted in loss of gland function. Many bovine mastitis vaccines for Staphylococcus aureus have used inactivated whole... The Y161F Substitution of Hemagglutinin Increases Antigenic Thermostability and Improves Yields of Influenza A Viruses Published: 9/6/2024 Inventor(s): Xiu-Feng (Henry) Wan, Feng Wen Background Vaccination has been the most efficient and economical strategy for preventing influenza virus infection and controlling disease spread among hosts. A high yield vaccine seed strain is required for timely vaccine manufacture and is thus a critical component of a successful influenza vaccination program. Unfortunately, it is not uncommon... mRNA Treatment to Induce Expression of Molecules to Prevent or Treat Tritrichomonas Foetus Infection in Bulls Published: 11/12/2024 Inventor(s): Amelia Woolums, Elmer King, Merrilee Thoresen Background Bulls and cows are susceptible to reproductive system infection by the protozoal parasite Tritrichomonas foetus (T. foetus). Infected cows are unable to deliver healthy calves, and they can become infected by bulls that, despite showing no signs of the disease, are capable of transmitting the infection to cows. The failure of cows to deliver... mRNA Therapy to Induce Expression of Molecules to Prevent or Treat Infectious Respiratory Disease in Cattle Published: 9/5/2024 Inventor(s): Amelia Woolums Background Infectious respiratory disease in cattle is the most common cause of sickness and death in many types of cattle in the United States and around the world. It is caused by one or more of multiple different viruses and/or bacteria. Technology Overview Bovine respiratory disease (BRD) is the leading cause of sickness and death in many types... mRNA Treatment to Induce Expression of Relaxin for Reproductive Applications in Animals and Humans Published: 9/9/2024 Inventor(s): Peter Ryan, Amelia Woolums, Elmer King, Merrilee Thoresen, Federico Hoffmann Background Female cattle and other animals, including humans, sometimes have trouble delivering their young (dystocia) at the time they are due because of inadequate relaxation or size of the mother's reproductive tract. Such situations can lead to difficult deliveries that may be harmful to the mother or the offspring. They may also require surgery... Increased Expression of Hyperpolarization-activated Cyclic Nucleotidgated Channel 4 (HCN4) in Airway Muscle During Naturally Occuring Asthma-like Disease Directs Pharmacologic Modulation of Funny Current Pathways to Modify Bronchial Tone... Published: 9/9/2024 Inventor(s): Cyprianna Swiderski, Courtney Hunter TREM1, HMBGB1 and PGLYRP1 Antagonism: Therapeutics for Severe and Neutrophilic Asthma in Horses and Humans Overview of Technology Therapeutics for severe and neutrophilic asthma in horses and humans Background of Technology HMBGI signaling, TREM1 expression and signaling and PGLYRP1 expression are all increased in the lung biopsies of horses with... TREM1, HMGB1, and PGLYRP1 antagonism: therapeutics for severe and neutrophilic asthma in horses and humans Published: 9/9/2024 Inventor(s): Cyprianna Swiderski Overview of Technology: Therapeutics for severe and neutrophilic asthma in horses and humans Background on Technology: HMBGI signaling, TREM1 expression and signaling and PGLYRP1 expression are all increased in the lung biopsies of horses with severe/neutrophilic asthma exacerbation. Increases in HMGB1 and TREM1 have also been identified in... Utilization of Oleaginous Microorganisms as a Nutritional Supplement for Animals Published: 9/9/2024 Inventor(s): Janet Donaldson, Jeffery Carroll Overview of Technology This technology introduces the benefit of the lipid producing Enterobacter sp. bacterium as an additive to livestock feed or water which, when consumed, produces a supplemental energy source for animals. Background The cost of livestock feed attributes the largest economic investment in livestock care, aside from the investment...